The two key mistakes you're making when applying niacinamide, according to experts

Not reaping the rewards from your go-to niacinamide serum? These common application faux pas could be to blame...

A close up of a clear glass pipette dripping a clear liquid, against a pink backdrop - to illustrate niacinamide mistakes when applying/ in a cream, white and grey marble-effect template
(Image credit: Getty Images/Mariya Borisova)

While niacinamide is beloved for its anti-inflammatory and skin barrier-boosting properties, the ingredient isn't without its drawbacks - especially where these niacinamide mistakes are concerned...

When it comes to the best niacinamide serums and best hyaluronic serums, they can seem like an easy addition to your skincare routine for glowing and healthy skin. And while niacinamide particularly, can certainly be classed as a holy grail ingredient, sadly seeing the benefits isn't as simple as patting it into your skin and saying "job done." Correct application is key and there are several common mistakes to avoid in that department.

So, to that end, we've asked three experts to outline all the niacinamide missteps to be aware of - and how to apply the powerhouse glow-giver for the best results...

The two common niacinamide mistakes to avoid

For those who don't know, niacinamide is a form of vitamin B3 and, as Dermatica's Medical Director Dr Catriona Maybury explains: "has been shown to improve fine lines and wrinkles, fade hyperpigmentation, increase ceramide production (for hydration) and reduce inflammation and redness associated with acne."

Dr Maryam Zamani, founder of MZ SKIN and leading Oculoplastic Surgeon also notes that: "Incorporating niacinamide into your routine can help improve overall skin health by enhancing barrier function, regulating cell metabolism, improving elasticity, reducing pigmentation, and soothing inflammation."

As mentioned, niacinamide is good for acne as it can help to soothe inflammation and reduce oil production, as well as help to strengthen your skin's natural barrier. So, it's indeed quite a dreamy ingredient for those looking to achieve clearer and more radiant skin. But that said, like with the known hyaluronic acid mistakes, it's important to know how not to apply it...

1. Applying it over creams

Your product order is key for building an effective skincare routine and this is one area, Advanced Facialist Mariam Abbas says many people go wrong with niacinamide.

"Niacinamide (vitamin B3) is a water-based antioxidant/vitamin," explains Abbas, "so applying it over a cream or lipid-based moisturiser will prevent absorption."

If you do however want to incorporate the ingredient into the latter stages of your skincare steps - or even your makeup routine - products like the Glow Recipe Watermelon Glow Niacinamide Dew Drops (which also features hyaluronic acid and glycerin) can be used as a primer, mixed with foundation and added as a glassy highlighter.

2. Using it with incompatible ingredients

Using niacinamide with other potent and active ingredients can also be detrimental. As Dr Zamani explains: "It is important to consider what other skincare ingredients you are mixing niacinamide with as certain products, like an AHA, may react negatively together and cause irritation to the skin.

"By being mindful of these mistakes and following the recommendations for niacinamide application, you can maximize its benefits for your skin while minimizing the risk of adverse reactions."

Abbas also adds that, "even though niacinamide has an anti-inflammatory effect on the skin and it is usually very well tolerated, it should not be used in very high concentrations at the same time as other actives such as vitamin A."

In the niacinamide vs hyaluronic acid debate though, the two ingredients can be used together, to moisturise and hydrate the skin. Equally, niacinamide and vitamin C can also be used side by side, so the former is very much a versatile ingredient - but it's crucial to know what it's not compatible with and adjust accordingly.

How to apply niacinamide correctly

So now we know what not to do, how do we apply niacinamide correctly?

Dr Zamani says: "An effective, simple skin care routine is essential. I would start with a gentle cleanse to “Reveal” the skins foundations. Next, enhance the skin: at this step, I would introduce your preferred niacinamide serum, taking a focus on areas where you have specific concerns - such as uneven skin tone or texture. Allow some time to fully absorb into your skin before applying any additional skincare products. And finally, protect the skin by applying an SPF."

Abbas also notes to "use it in concentrations of 5%-10% after cleansing and before moisturising."

Naomi Jamieson
Digital Beauty Writer

Naomi is a Digital Beauty Writer from woman&home, where she covers everything from skincare to fragrance but specialises, particularly, in makeup and nail trends. Through her work, Naomi gets to share her trend expertise and share her own shopping recommendations and product reviews. Previously, she worked as a Lifestyle News Writer for My Imperfect Life magazine, where she used her savvy for TikTok to bring readers the latest beauty buzzwords, fashion movements and must-have products. 

Before that, Naomi split her time between both GoodTo and My Imperfect Life, whilst training for her Gold Standard diploma in Journalism with the NCTJ, for which she earned a Distinction. Interestingly though, Naomi actually has a background in design, having studied illustration at Plymouth University but leapt into the media world in 2020, after always having a passion for writing. Now, when she isn’t reporting on the best perfumes and latest beauty releases, you can find her drinking copious cups of coffee, drawing and probably online shopping...