Does Vitamin C irritate your skin? I’ve found the perfect alternative - and my skin's never looked glowier

This affordable buy offers all the radiance of Vit C serums, without breakouts or sensitivity

An image of senior beauty editor Rhiannon Derbyshire with glowing skin alongside a photo of her holding the Cetaphil Advanced Defence serum
(Image credit: Future/Rhiannon Derbyshire)

As a beauty editor with a slightly lazy approach to skincare, my job involves navigating a fair amount of ‘do as I say, not as I do’. I don’t really think an eye cream is necessary. I’ve disgusted a lot of trichologists by telling them I only wash my hair once a week.

None of these little rebellions particularly worry me - I’m confident in my ability to reach my skin goals (plump, dewy skin) and how to achieve them (enough hyaluronic acid serum to sink the Titanic). One little miss does bother me, though - I don’t use Vitamin C serum.

Even the best Vitamin C serums break me out, and I’ve tried them all. They irritate my skin and cause breakouts almost immediately. I resigned myself to being antioxidant-less and vulnerable to the perils of pollution until I found this powerful protective serum that doesn’t rely on Vitamin C as an ingredient. The best bit? It’s only £26.50.

I know - in the grand scheme of things, my intolerance of Vitamin C isn’t actually that concerning. Having interviewed plenty of skin experts and dermatologists over the years, though, it does feel like I’m breaking quite a crucial rule.

If you know what vitamin C does, you’ll know that it’s an antioxidant that protects skin from pollution, while also helping to heal damage that’s already occurred. Vitamin C is one of the best-known and most commonly used antioxidants, but the downside is that it can irritate sensitive skin types.

Lucky me, then, that I stumbled upon Cetaphil’s Advanced Defence Serum, which is sold as an alternative to Vitamin C for sensitive skin - something I’d never even considered seeking out. I thought I was doomed to be spotty from blemishes or pigmentation forevermore.

I tried it on a whim, half expecting a breakout or a reaction, and was happy to note that it never arrived. I was happier still, a week later, when I noticed how much brighter and fresher my skin looked. I found myself using less concealer, or sometimes skipping base altogether.

Two images of senior beauty editor Rhiannon Derbyshire with glowing skin - one without makeup, one with makeup

Rhiannon without (L) and with makeup, after using the serum for two weeks

(Image credit: Future/Rhiannon Derbyshire)

Instead of pesky Vitamin C, this serum is powered by a blend of Gallic Acid and Vitamin E. These, working in tandem, have been proven to be two times more effective than Vitamin C, minus any irritation - so it’s no wonder I saw the results so powerfully (and so quickly).

Another thing I never enjoyed about Vitamin C serums was the texture. They were sticky or oddly gritty, and never sat nicely on my skin. Cetaphil’s Advanced Defence Serum is positively silky. It glides on beautifully and sinks in almost immediately, never leaving skin feeling tacky or pilling.

This might also be down to the ingredients list - pairing it with my good friend hyaluronic acid and tightening niacinamide makes it a clever multitasker that provides multiple skin wins.

An image of senior beauty editor Rhiannon holding the Cetaphil Advanced Defence serum, and showing the swatch of the serum on her hand

(Image credit: Future/Rhiannon Derbyshire)

If you found Vitamin C irritating or hard to fit into your routine, I'm betting you'll enjoy using Cetaphil's Advanced Defence Serum much more. I'm certainly hooked.

Rhiannon Derbyshire
Senior Beauty Editor

Rhiannon Derbyshire is the Senior Beauty Editor for Woman & Home.

She started interning for glossy magazines in 2011 while working alongside her Fashion Journalism degree. There, she was lured to the beauty desk, seduced by red lipsticks, posh shampoos, and every skincare product imaginable. 15+ years into her career, she now writes about skincare, haircare and makeup for six national titles and interviews celebrities, experts and brand founders. She oversees and judges products for the Woman & Home skin, hair and beauty awards, testing hundreds of products yearly.

With 3A curls, Rhiannon specialises in writing about curly hair routines and has a penchant for red lipsticks and minimalist skincare routines - with a bit of LED therapy thrown in.

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