Hi Nzemylou
This is my first ever post to the forum and your post immediate struck a cord with me. I am 44 and we have an 8 yr old boy who for years and years asked for a brother or sister but recently has stopped asking. He is happy, well adjusted, popular, confidence and intelligent with loads of friends and a massive social network.
We started 'trying' for another when my son was 1 ((i was 36) and when he was 3 we embarked upon IVF only to be told, at 38, that I had no eggs left and i was entering menopause. I grieved for 4 years until i was your age, 42, when I became quite desperate and started to research about donor eggs. We have been trying to conceive with donor eggs now for two years and the miracle has finally happened. I am 6w1d pregnant with twins. OMG! 
I just want you to know that, firstly, at 42, you can get pregnant but your chances of success are diminishing rapidly - perhaps you might consider fertility treatment (i have an acquaintance who's 46 and just pregnant with her first IVF run). And yes, your chances of Downs are higher due to the chromosonal age of your eggs so you need to consider how you would react to any abnormal news.
My donor is only 22 but, like Marie50, if we find some adnormalities, we will terminate, horrendous as that may be. We are not spring chickens (although we are extremely young at heart and most people can't believe we're in our 40s) and debatable as it is, i do not want to spend the rest of my life looking after childen. Another 20 years is acceptable though.
I appreciate the idea of donor eggs is abhorent to a lot of people and i have had some nasty thoughtless comments from my neighbour yesterday about my age when i told her our special news, and it did take me 4 years to get my head around it, but it's another option open to you.
Best of luck whatever you choose to do.
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