After a long break would you feel happier starting with something simple just to get your confidence up and some experience on your CV? Find quite a basic job in your chosen field, impress people by how fab you are, make some contacts and take it from there..
i.e. get on a register for casual staff at big events, then you're not committed to a long-term job and you can build up your skills ... maybe follow that with a college qualification, then move onwards and upwards!
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