In the last year we've lost my FIL and my BIL (mid 40's) has been diagnosed with something that is likely to be terminal and now my OH has to have a CT scan as his migraines have been getting more frequent and he seems to have at least a mild a headache more days than he doesn't. We've thought long and hard and have decided that we won't turn down any new opportunities or experiences (providing of course it's legal) - it's worth trying anything at least once (and maybe twice if we like it!). Life is most certainly too short.